1. Reitsma S, oude Egbrink MG, Vink H, van den Berg BM, Passos VL, Engels W, Slaaf DW, van Zandvoort MA: Endothelial glycocalyx structure in the intact carotid artery: a two-photon laser scanning microscopy study, J Vasc Res 2011, 48:297-306
  2. Reitsma S, Oude Egbrink MG, Heijnen VV, Megens RT, Engels W, Vink H, Slaaf DW, van Zandvoort MA: Endothelial glycocalyx thickness and platelet-vessel wall interactions during atherogenesis, Thromb Haemost 2011, 106:939-946
  3. Constantinescu A, Spaan JA, Arkenbout EK, Vink H, Vanteeffelen JW: Degradation of the endothelial glycocalyx is associated with chylomicron leakage in mouse cremaster muscle microcirculation, Thromb Haemost 2011, 105:790-801
  4. VanTeeffelen JW, Brands J, Vink H: Agonist-induced impairment of glycocalyx exclusion properties: contribution to coronary effects of adenosine, Cardiovasc Res 2010, 87:311-319
  5. Snoeijs MG, Vink H, Voesten N, Christiaans MH, Daemen JW, Peppelenbosch AG, Tordoir JH, Peutz-Kootstra CJ, Buurman WA, Schurink GW, van Heurn LW: Acute ischemic injury to the renal microvasculature in human kidney transplantation, Am J Physiol Renal Physiol 2010, 299:F1134-1140
  6. Meuwese MC, Broekhuizen LN, Kuikhoven M, Heeneman S, Lutgens E, Gijbels MJ, Nieuwdorp M, Peutz CJ, Stroes ES, Vink H, van den Berg BM: Endothelial surface layer degradation by chronic hyaluronidase infusion induces proteinuria in apolipoprotein E-deficient mice, PLoS One 2010, 5:e14262
  7. Broekhuizen LN, Lemkes BA, Mooij HL, Meuwese MC, Verberne H, Holleman F, Schlingemann RO, Nieuwdorp M, Stroes ES, Vink H: Effect of sulodexide on endothelial glycocalyx and vascular permeability in patients with type 2 diabetes mellitus, Diabetologia 2010, 53:2646-2655
  8. Brands J, Spaan JA, Van den Berg BM, Vink H, VanTeeffelen JW: Acute attenuation of glycocalyx barrier properties increases coronary blood volume independently of coronary flow reserve, Am J Physiol Heart Circ Physiol 2010, 298:H515-523
  9. van den Berg BM, Spaan JA, Vink H: Impaired glycocalyx barrier properties contribute to enhanced intimal low-density lipoprotein accumulation at the carotid artery bifurcation in mice, Pflugers Arch 2009, 457:1199-1206
  10. Nieuwdorp M, Meuwese MC, Mooij HL, van Lieshout MH, Hayden A, Levi M, Meijers JC, Ince C, Kastelein JJ, Vink H, Stroes ES: Tumor necrosis factor-alpha inhibition protects against endotoxin-induced endothelial glycocalyx perturbation, Atherosclerosis 2009, 202:296-303
  11. Meuwese MC, Mooij HL, Nieuwdorp M, van Lith B, Marck R, Vink H, Kastelein JJ, Stroes ES: Partial recovery of the endothelial glycocalyx upon rosuvastatin therapy in patients with heterozygous familial hypercholesterolemia, J Lipid Res 2009, 50:148-153
  12. Grundmann S, Schirmer SH, Hekking LH, Post JA, Ionita MG, de Groot D, van Royen N, van den Berg B, Vink H, Moser M, Bode C, de Kleijn D, Pasterkamp G, Piek JJ, Hoefer IE: Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adhesion in arteriogenesis, J Cell Mol Med 2009, 13:3463-3474
  13. Broekhuizen LN, Mooij HL, Kastelein JJ, Stroes ES, Vink H, Nieuwdorp M: Endothelial glycocalyx as potential diagnostic and therapeutic target in cardiovascular disease, Curr Opin Lipidol 2009, 20:57-62
  14. VanTeeffelen JW, Constantinescu AA, Brands J, Spaan JA, Vink H: Bradykinin- and sodium nitroprusside-induced increases in capillary tube haematocrit in mouse cremaster muscle are associated with impaired glycocalyx barrier properties, J Physiol 2008, 586:3207-3218
  15. VanTeeffelen JW: How to prevent leaky vessels during reperfusion? Just keep that glycocalyx sealant in place!, Crit Care 2008, 12:167
  16. Van Teeffelen J, Vink H: Capillary blood volume increase in already perfused capillaries: role for glycocalyx modulation, J Appl Physiol 2008, 104:895
  17. Noble MI, Drake-Holland AJ, Vink H: Hypothesis: arterial glycocalyx dysfunction is the first step in the atherothrombotic process, Qjm 2008, 101:513-518
  18. Nijenhuis N, Mizuno D, Schmidt CF, Vink H, Spaan JA: Microrheology of hyaluronan solutions: implications for the endothelial glycocalyx, Biomacromolecules 2008, 9:2390-2398
  19. Nieuwdorp M, Meuwese MC, Mooij HL, Ince C, Broekhuizen LN, Kastelein JJ, Stroes ES, Vink H: Measuring endothelial glycocalyx dimensions in humans: a potential novel tool to monitor vascular vulnerability, J Appl Physiol 2008, 104:845-852
  20. VanTeeffelen JW, Brands J, Jansen C, Spaan JA, Vink H: Heparin impairs glycocalyx barrier properties and attenuates shear dependent vasodilation in mice, Hypertension 2007, 50:261-267
  21. Van Teeffelen JW, Brands J, Stroes ES, Vink H: Endothelial glycocalyx: sweet shield of blood vessels, Trends Cardiovasc Med 2007, 17:101-105
  22. Reitsma S, Slaaf DW, Vink H, van Zandvoort MA, oude Egbrink MG: The endothelial glycocalyx: composition, functions, and visualization, Pflugers Arch 2007, 454:345-359
  23. Nieuwdorp M, Holleman F, de Groot E, Vink H, Gort J, Kontush A, Chapman MJ, Hutten BA, Brouwer CB, Hoekstra JB, Kastelein JJ, Stroes ES: Perturbation of hyaluronan metabolism predisposes patients with type 1 diabetes mellitus to atherosclerosis, Diabetologia 2007, 50:1288-1293
  24. van den Berg BM, Spaan JA, Rolf TM, Vink H: Atherogenic region and diet diminish glycocalyx dimension and increase intima-to-media ratios at murine carotid artery bifurcation, Am J Physiol Heart Circ Physiol 2006, 290:H915-920
  25. van den Berg BM, Nieuwdorp M, Stroes ES, Vink H: Glycocalyx and endothelial (dys) function: from mice to men, Pharmacol Rep 2006, 58 Suppl:75-80
  26. van den Berg B, Vink H: Glycocalyx perturbation: cause or consequence of damage to the vasculature?, Am J Physiol Heart Circ Physiol 2006, 290:H2174-2175
  27. Nieuwdorp M, van Haeften TW, Gouverneur MC, Mooij HL, van Lieshout MH, Levi M, Meijers JC, Holleman F, Hoekstra JB, Vink H, Kastelein JJ, Stroes ES: Loss of endothelial glycocalyx during acute hyperglycemia coincides with endothelial dysfunction and coagulation activation in vivo, Diabetes 2006, 55:480-486
  28. Nieuwdorp M, Mooij HL, Kroon J, Atasever B, Spaan JA, Ince C, Holleman F, Diamant M, Heine RJ, Hoekstra JB, Kastelein JJ, Stroes ES, Vink H: Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes, Diabetes 2006, 55:1127-1132
  29. Han Y, Weinbaum S, Spaan JA, Vink H: Large-deformation analysis of the elastic recoil of fibre layers in a Brinkman medium with application to the endothelial glycocalyx, the Journal of Fluid Mechanics 2006, 554:217-235
  30. Gouverneur M, Spaan JA, Pannekoek H, Fontijn RD, Vink H: Fluid shear stress stimulates incorporation of hyaluronan into endothelial cell glycocalyx, Am J Physiol Heart Circ Physiol 2006, 290:H458-452
  31. Gouverneur M, Berg B, Nieuwdorp M, Stroes E, Vink H: Vasculoprotective properties of the endothelial glycocalyx: effects of fluid shear stress, J Intern Med 2006, 259:393-400
  32. Zuurbier CJ, Demirci C, Koeman A, Vink H, Ince C: Short-term hyperglycemia increases endothelial glycocalyx permeability and acutely decreases lineal density of capillaries with flowing red blood cells, J Appl Physiol 2005, 99:1471-1476
  33. VanTeeffelen JW, Dekker S, Fokkema DS, Siebes M, Vink H, Spaan JA: Hyaluronidase treatment of coronary glycocalyx increases reactive hyperemia but not adenosine hyperemia in dog hearts, Am J Physiol Heart Circ Physiol 2005, 289:H2508-2513
  34. VanTeeffelen JW, Constantinescu AA, Vink H, Spaan JA: Hypercholesterolemia impairs reactive hyperemic vasodilation of 2A but not 3A arterioles in mouse cremaster muscle, Am J Physiol Heart Circ Physiol 2005, 289:H447-454
  35. van Haaren PM, VanBavel E, Vink H, Spaan JA: Charge modification of the endothelial surface layer modulates the permeability barrier of isolated rat mesenteric small arteries, Am J Physiol Heart Circ Physiol 2005, 289:H2503-2507
  36. Nieuwdorp M, Meuwese MC, Vink H, Hoekstra JB, Kastelein JJ, Stroes ES: The endothelial glycocalyx: a potential barrier between health and vascular disease, Curr Opin Lipidol 2005, 16:507-511
  37. Weinbaum S, Zhang X, Han Y, Vink H, Cowin SC: Mechanotransduction and flow across the endothelial glycocalyx, Proc Natl Acad Sci U S A 2003, 100:7988-7995
  38. van Haaren PM, VanBavel E, Vink H, Spaan JA: Localization of the permeability barrier to solutes in isolated arteries by confocal microscopy, Am J Physiol Heart Circ Physiol 2003, 285:H2848-2856
  39. van den Berg BM, Vink H, Spaan JA: The endothelial glycocalyx protects against myocardial edema, Circ Res 2003, 92:592-594
  40. Mochizuki S, Vink H, Hiramatsu O, Kajita T, Shigeto F, Spaan JA, Kajiya F: Role of hyaluronic acid glycosaminoglycans in shear-induced endothelium-derived nitric oxide release, Am J Physiol Heart Circ Physiol 2003, 285:H722-726
  41. Constantinescu AA, Vink H, Spaan JA: Endothelial cell glycocalyx modulates immobilization of leukocytes at the endothelial surface, Arterioscler Thromb Vasc Biol 2003, 23:1541-1547
  42. Constantinescu AA, Vink H, Spaan JA: Elevated capillary tube hematocrit reflects degradation of endothelial cell glycocalyx by oxidized LDL, Am J Physiol Heart Circ Physiol 2001, 280:H1051-1057
  43. Vink H, Duling BR: Capillary endothelial surface layer selectively reduces plasma solute distribution volume, Am J Physiol Heart Circ Physiol 2000, 278:H285-289
  44. Vink H, Constantinescu AA, Spaan JA: Oxidized lipoproteins degrade the endothelial surface layer : implications for platelet-endothelial cell adhesion, Circulation 2000, 101:1500-1502
  45. Vink H, Duling BR: Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries, Circ Res 1996, 79:581-589
  46. Vink H, Wieringa PA, Spaan JA: Evidence that cell surface charge reduction modifes capillary red cell velocity-flux relationships in hamster cremaster muscle, J Physiol 1995, 489 ( Pt 1):193-201



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